Segments are processed serially when each segment experiment differs by temperature or residence time.

Segments are processed in a serial/parallel methodology, which signigicantly increases throughput when sequential segments share the same temperature and residence time. Segments may vary by stoichiometry for optimization and/or as in screening and library production composition of matter.

Reactions are easily scaled in segmented flow by using the Prep Mode, which creates hundreds of segments based the appropriate composition and injects segments using serial/parallel methodology with little to no Transport Solvent between segments. Immiscible spacers are used in each segment to minimize diffusion.